2015

Dale T, Clarke PA, Esdar C, Waalboer D, Adeniji-Popoola O, Ortiz-Ruiz MJ, Mallinger A, Samant RS, Czodrowski P, Musil D, Schwarz D, Schneider K, Stubbs M, Ewan K, Fraser E, TePoele R, Court W, Box G, Valenti M, de Haven Brandon A, Gowan S, Rohdich F, Raynaud F, Schneider R, Poeschke O, Blaukat A, Workman P, Schiemann K, Eccles SA, Wienke D, Blagg J; Nat Chem Biol.  "A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease" 2015 11(12), 973-80

Czodrowski P, Hölzemann G, Barnickel G, Greiner H, Musil D; J Med Chem „Selection of fragments for kinase inhibitor design: decoration is key“ 2015 58(1), 457-65

 

2014

Grädler U, Czodrowski P,  Tsaklakidis C, Klein M, Werkmann D, Lindemann S, Maskos K, Leuthner B; Bioorg Med Chem Lett "Structure-based optimization of non-peptidic Cathepsin D inhibitors" 2014, 24(17):4141-50

Czodrowski P; J Comput Aided Mol Des "Count on kappa" 2014, 28(11):1049-55

Neeb M, Czodrowski P  Heine A, Barandun LJ, Hohn C, Diederich F, Klebe G; J Med Chem „Chasing protons: how isothermal titration calorimetry, mutagenesis, and pKa calculations trace the locus of charge in ligand binding to a tRNA-binding enzyme“ 2014, 57(13):5554-65

Samel SA, Czodrowski P, Essen LO; Acta Crystallogr D Biol Crystallogr  „Structure of the epimerization domain of tyrocidine synthetase A“ 2014, 70(Pt 5):1442-52

 

2013

Czodrowski P; J Chem Inf Model. 2013, 53(9):2240-51 „hERG me out.“

Kokh DB, Richter S, Henrich S, Czodrowski P, Rippmann F, Wade RC; J Chem Inf Model. 2013, 53(5):1235-52. „TRAPP: a tool for analysis of transient binding pockets in proteins“

 

2012

Czodrowski P; Bioorg Med Chem. 2012, 20(18):5453-60 „Who cares for the protons?“

 

2011

Czodrowski P; Proteins. 2011, 79(12):3299-305 „Blind, one-eyed, or eagle-eyed? pKa calculations during blind predictions with staphylococcal nuclease.“

 

<2011

Czodrowski P, Kriegl JM, Scheuerer S, Fox T; Expert Opin Drug Metab Toxicol. 2009, 5(1):15-27 “Computational approaches to predict drug metabolism“

Steuber H, Czodrowski P, Sotriffer CA, Klebe G; J Mol Biol. 2007, 373(5):1305-20 “Tracing changes in protonation: a prerequisite to factorize thermodynamic data of inhibitor binding to aldose reductase.”

Czodrowski P, Sotriffer CA, Klebe G; J Chem Inf Model. 2007, 47(4):1590-8 “Atypical protonation states in the active site of HIV-1 protease: a computational study.”

Dolinsky TJ, Czodrowski P, Li H, Nielsen JE, Jensen JH, Klebe G, Baker NA; Nucleic Acids Res. 2007, 35(Web Server issue):W522-5. “PDB2PQR: expanding and upgrading automated preparation of biomolecular structures formolecular simulations.”

Czodrowski P, Sotriffer CA, Klebe G; J Mol Biol. 2007, 367(5):1347-56 “Protonation changes upon ligand binding to trypsin and thrombin: structural interpretation based on pKa calculations and ITC experiments.”

Czodrowski P, Dramburg I, Sotriffer CA, Klebe G; Proteins. 2006, 65(2):424-37 „Development, validation, and application of adapted PEOE charges to estimate pKa values of functional groups in protein-ligand complexes.“

Wittelsberger A, Corich M, Thomas BE, Lee BK, Barazza A, Czodrowski P, Mierke DF, Chorev M, Rosenblatt M; Biochemistry. 2006, 45(7):2027-34 “The mid-region of parathyroid hormone (1-34) serves as a functional docking domain in receptor activation.”